We investigated the role of ferroptosis in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). By using an experimental model, we applied treatments with deferoxamine (DFO) and edaravone (EDA) to inhibit ferroptosis.
Our findings revealed that targeting ferroptosis may reduce inflammation, fibrosis, and mast cell activity, potentially easing pelvic pain associated with CP/CPPS. These results highlight a new pathway for treating this challenging condition, offering hope for improved management strategies.
Read More
7
Long-acting contraceptives offer health benefits
Added health benefits of the levonorgestrel contraceptive intrauterine system and other hormonal contraceptive delivery systems.
We discovered that hormonal contraceptives, particularly long-acting systems like the levonorgestrel-releasing intrauterine device, provide significant non-contraceptive health benefits.
These benefits include the treatment of pelvic pain, especially in cases related to endometriosis, as well as management of heavy menstrual bleeding and iron deficiency.
Research highlights that these contraceptives are effective options for addressing various gynecological disorders beyond birth control.
Read More
5
Iron patch offers similar pain relief
Comparing the analgesic effect of heat patch containing iron chip and ibuprofen for primary dysmenorrhea: a randomized controlled trial.
We explored the effectiveness of a heat patch containing iron chips compared to ibuprofen for alleviating primary dysmenorrhea. In our randomized controlled trial involving 147 students, we examined pain severity and emotional impact using a standardized questionnaire.
Although we found that the heat patch provided comparable relief to ibuprofen, the differences in pain severity were not significant. This suggests that while the heat patch is a viable option, it may not be markedly more effective than ibuprofen for managing menstrual pain.
Read More
Most Useful Reviews
9
Reduced pelvic pain
2 people found this helpful
On discovering Dr. Fujikawa's book, I started taking iron for severe menstrual pain and PMS. Over three years, it has greatly eased my lower back pain and reduced dizziness when standing and morning fatigue. I worry about running out of this supplement!
Read More
9
No pelvic pain
2 people found this helpful
This product is fantastic! It helped maintain my haemoglobin levels during pregnancy. Doctors were astonished at the consistent results. I took two capsules daily and in later stages increased to three. I feel great, and I’ve forgotten what menstrual pain feels like!
Read More
8
No pelvic pain
2 people found this helpful
Within a month of taking iron, I noticed my skin improved; dryness disappeared, and cracks on my heels vanished. My drowsiness and menstrual pains have also lessened. It’s remarkable what iron can achieve!
We investigated the role of ferroptosis in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). By using an experimental model, we applied treatments with deferoxamine (DFO) and edaravone (EDA) to inhibit ferroptosis.
Our findings revealed that targeting ferroptosis may reduce inflammation, fibrosis, and mast cell activity, potentially easing pelvic pain associated with CP/CPPS. These results highlight a new pathway for treating this challenging condition, offering hope for improved management strategies.
Read More
7
Long-acting contraceptives offer health benefits
Added health benefits of the levonorgestrel contraceptive intrauterine system and other hormonal contraceptive delivery systems.
We discovered that hormonal contraceptives, particularly long-acting systems like the levonorgestrel-releasing intrauterine device, provide significant non-contraceptive health benefits.
These benefits include the treatment of pelvic pain, especially in cases related to endometriosis, as well as management of heavy menstrual bleeding and iron deficiency.
Research highlights that these contraceptives are effective options for addressing various gynecological disorders beyond birth control.
Read More
7
Goserelin enhances hemoglobin but not pain
Goserelin acetate 10.8 mg plus iron versus iron monotherapy prior to surgery in premenopausal women with iron-deficiency anemia due to uterine leiomyomas: results from a Phase III, randomized, multicenter, double-blind, controlled trial.
We aimed to understand the impact of adding goserelin acetate to iron treatment in premenopausal women facing iron-deficiency anemia due to uterine fibroids.
In this Phase III trial, participants received either goserelin with iron or just iron over 12 weeks, followed by surgery. While women given goserelin showed higher hemoglobin levels, we didn’t find a significant improvement in symptoms like pelvic pain.
Overall, while goserelin helped with blood levels, it didn't make a noticeable difference in alleviating pelvic discomfort.
Read More
5
Lactoferrin benefits menstrual distress
Effects of a Bovine Lactoferrin Formulation from Cow's Milk on Menstrual Distress in Volunteers: A Randomized, Crossover Study.
Our study examined the effects of a lactoferrin formulation derived from cow's milk on menstrual symptoms in healthy women.
Conducted as a double-blind, randomized, placebo-controlled trial, we enrolled thirty-five Japanese volunteers who received either the iron-lactoferrin complex or a placebo.
While our findings showed improvements in psychological symptoms related to menstrual distress, such as reduced MDQ scores, other measures—like pain and quality of life—did not vary significantly.
Notably, no side effects were reported, suggesting this treatment could help with psychological discomfort linked to dysmenorrhea.
Read More
5
Iron patch offers similar pain relief
Comparing the analgesic effect of heat patch containing iron chip and ibuprofen for primary dysmenorrhea: a randomized controlled trial.
We explored the effectiveness of a heat patch containing iron chips compared to ibuprofen for alleviating primary dysmenorrhea. In our randomized controlled trial involving 147 students, we examined pain severity and emotional impact using a standardized questionnaire.
Although we found that the heat patch provided comparable relief to ibuprofen, the differences in pain severity were not significant. This suggests that while the heat patch is a viable option, it may not be markedly more effective than ibuprofen for managing menstrual pain.
Read More
User Reviews
USERS' SCORE
Good
Based on 26 Reviews
8.4
All Reviews
Positive Reviews
Negative Reviews
9
Reduced pelvic pain
2 people found this helpful
On discovering Dr. Fujikawa's book, I started taking iron for severe menstrual pain and PMS. Over three years, it has greatly eased my lower back pain and reduced dizziness when standing and morning fatigue. I worry about running out of this supplement!
Read More
9
No pelvic pain
2 people found this helpful
This product is fantastic! It helped maintain my haemoglobin levels during pregnancy. Doctors were astonished at the consistent results. I took two capsules daily and in later stages increased to three. I feel great, and I’ve forgotten what menstrual pain feels like!
Read More
8
No pelvic pain
2 people found this helpful
Within a month of taking iron, I noticed my skin improved; dryness disappeared, and cracks on my heels vanished. My drowsiness and menstrual pains have also lessened. It’s remarkable what iron can achieve!
Read More
9
Improved OCD symptoms
1 people found this helpful
I've been taking this iron for my anaemia, and significantly, my obsessive-compulsive disorder symptoms have improved. I no longer have the same compulsions, making daily life much easier. I plan to continue with this supplement as it has made a positive impact.
Read More
9
Eliminated pain
1 people found this helpful
This supplement has worked wonders! Taking it before and during menstruation has eradicated my pelvic pain, leading to a much more comfortable experience. I'm thrilled with the results!
Pelvic pain is a broad term that describes discomfort occurring in the lower abdomen or pelvic region. It can stem from various underlying conditions, involving reproductive organs, the urinary tract, or gastrointestinal issues. Common causes include menstrual cramps, endometriosis, pelvic inflammatory disease, ovarian cysts, and urinary tract infections. Additionally, pelvic pain can be acute, occurring suddenly and sharply, or chronic, lasting for six months or more, significantly impacting one’s quality of life.
Managing pelvic pain often begins with a thorough evaluation from a healthcare provider to determine the underlying causes. Treatment options can vary widely based on the diagnosis and may include medication for pain relief, physical therapy, lifestyle changes, or, in some cases, surgery. Lifestyle adjustments, such as heat therapy and relaxation techniques, can also provide relief. Given the diverse nature of pelvic pain, it’s essential for individuals experiencing persistent discomfort to consult a medical professional for an accurate diagnosis and personalized treatment plan.
Iron is a chemical element with the symbol Fe, derived from the Latin word "ferrum." It is a metal that is known for its strength and versatility, making it one of the most widely used materials in construction, manufacturing, and various industrial applications. Iron is the fourth most abundant element in the universe by mass and is primarily obtained through the mining of iron ores, such as hematite and magnetite. Once mined, it undergoes processes like smelting and refining to produce usable forms like cast iron, wrought iron, and steel.
In addition to its industrial uses, iron is also crucial for human health, as it plays a significant role in the production of hemoglobin, the protein in red blood cells responsible for transporting oxygen throughout the body. A deficiency in iron can lead to anemia, characterized by fatigue and weakened immunity. Overall, iron is a fundamental element that supports modern infrastructure and is vital for maintaining good health.
Based on user reviews, the time it typically takes to see results from this iron supplement for pelvic pain can vary. Many users report relief within a month of starting the supplement; for instance, one reviewer mentioned a significant reduction in menstrual pains after just four weeks of usage Read Review. Others have experienced improvements more gradually, with reports indicating relief only after consuming the entire first jar. For example, one individual noted considerable pain reduction after finishing their first jar of the supplement Read Review.
Additionally, long-term users have reported sustained benefits over several months, with some stating that they noticed decreased pelvic pain and improved overall well-being after consistent usage for up to a year Read Review. Overall, while initial results may be seen within weeks, significant improvements in pelvic pain seem to be achieved with ongoing use of the supplement.
Based on the available scientific research, one supplement, specifically iron-lactoferrin derived from cow's milk, has shown potential benefits for menstrual discomfort, although it primarily addresses psychological symptoms rather than physical pain associated with pelvic conditions. In a double-blind, randomized, placebo-controlled trial, participants experienced some improvements in psychological distress related to menstrual symptoms, but there was no significant impact on pain severity or overall quality of life metrics [2]. Additionally, while hormonal contraceptives, particularly long-acting options like the levonorgestrel-releasing intrauterine device, are effective in treating pelvic pain related to endometriosis, there’s no direct endorsement of dietary supplements for pelvic pain relief [3].
While some studies have explored treatments that indirectly relate to pelvic pain management, such as iron treatments combined with goserelin, the results did not indicate significant pain relief despite improved hemoglobin levels [5]. Therefore, the support for specific supplements in managing pelvic pain is limited, and most findings emphasize a need for further exploration rather than conclusive evidence of efficacy at this time.
Users of this iron supplement have reported a variety of improvements in their symptoms, particularly regarding pelvic pain, menstrual discomfort, fatigue, and overall energy levels. Many users have noted a significant reduction in menstrual pain, with one reviewer enthusiastically stating that taking the supplement has "eradicated my pelvic pain" during menstruation Read Review. Others have experienced relief in lower back pain, dizziness, and fatigue, highlighting a comprehensive improvement in their overall well-being after incorporating the supplement into their routines Read Review.
Furthermore, several long-term users have shared transformative experiences, noting enhancements in their energy and mood, as well as significant decreases in symptoms associated with iron deficiency, such as dizziness and menstrual pain Read Review. Remarkably, one user highlighted that within just weeks of starting the regimen, they felt revitalized and noticed their headaches had ceased entirely Read Review. While individual results can certainly vary, the overarching sentiment from user reviews suggests that many have found considerable relief and improved quality of life after using this iron supplement.
Users have reported positive experiences when combining this iron supplement with other supplement regimens to address pelvic pain. Several individuals mentioned specifically increasing their intake around their menstrual cycles; for example, one user indicated that they take one capsule daily and then raise the dosage to two capsules during their period, which significantly alleviated their pelvic pain and dizziness Read Review. Another reviewer echoed this sentiment, sharing that they consume three capsules at night along with vitamin C, resulting in a marked reduction in menstrual discomfort Read Review.
Moreover, there are reports of users having transformed their experiences around menstruation through consistent supplementation. For instance, one reviewer enthusiastically noted that taking the iron supplement before and during menstruation completely eradicated their pelvic pain Read Review. The combination of this iron supplement with thoughtful timing and possible pairing with vitamin C seems to enhance its effects for many, leading to significant benefits in managing pelvic pain and improving overall well-being.
Users report that finding the right dose of iron for treating pelvic pain can be quite beneficial. Many have experienced significant relief by taking different amounts based on their personal needs and the timing of their symptoms. For instance, one user indicated a dosage of two capsules daily, which they later increased to three during later stages of pregnancy, leading to a complete cessation of menstrual pain Read Review. Another user noted taking one capsule daily, with an increase to two before and during menstruation, which significantly alleviated their pelvic pain and dizziness Read Review.
In general, feedback suggests that a regimen involving regular doses, particularly around the time of menstruation, can be effective. For example, one user reported that taking one tablet at night and another during periods led to a complete reduction of tiredness and menstrual pain Read Review. Overall, it appears that users have found personalized adjustments in dosage may enhance their experience and help manage pelvic pain while addressing iron deficiency.
8
No pelvic pain
2 people found this helpful
Within a month of taking iron, I noticed my skin improved; dryness disappeared, and cracks on my heels vanished. My drowsiness and menstrual pains have also lessened. It’s remarkable what iron can achieve!
7.5
No more pain
1 people found this helpful
I only experienced relief after finishing the first jar, but now my pelvic pain has diminished considerably. I can sleep without painkillers, which is a great improvement!
9
Less fatigue
1 people found this helpful
After a year of taking this, I've experienced reduced fatigue and alleviated pelvic pain.
9
Eliminated pain
1 people found this helpful
This supplement has worked wonders! Taking it before and during menstruation has eradicated my pelvic pain, leading to a much more comfortable experience. I'm thrilled with the results!
9
Reduced pelvic pain
2 people found this helpful
On discovering Dr. Fujikawa's book, I started taking iron for severe menstrual pain and PMS. Over three years, it has greatly eased my lower back pain and reduced dizziness when standing and morning fatigue. I worry about running out of this supplement!
9
No pelvic pain
46 people found this helpful
I'm shocked by the results of taking this iron! After a year of low haemoglobin, linked to a poor iron diet, my doctor recommended iron supplements. I chose this chelated iron due to concerns about traditional options causing stomach issues. I took two tablets daily, along with apples and oranges. Within weeks, my headaches ceased and I felt much better; haemoglobin rose from 113 to 144! There were no side effects; no constipation, nausea, or stomach cramps, just benefits. I highly recommend this iron!
9
Alleviated pelvic pain
I usually take one capsule daily for my severe pelvic pain and iron deficiency anaemia, increasing to two capsules before and during my period. This helps with dizziness and alleviates my pelvic pain significantly!
7.5
Reduced pelvic pain
2 people found this helpful
This iron is easy to take. I consume three capsules at night with vitamin C. I’ve noticed a significant reduction in menstrual pain.
9
No pelvic pain
2 people found this helpful
This product is fantastic! It helped maintain my haemoglobin levels during pregnancy. Doctors were astonished at the consistent results. I took two capsules daily and in later stages increased to three. I feel great, and I’ve forgotten what menstrual pain feels like!
7.5
Less fatigue
1 people found this helpful
Since taking this iron supplement, my fatigue and menstrual pain have significantly reduced. I take one tablet nightly and another during periods, and I no longer experience tiredness or faintness.
5
Lactoferrin benefits menstrual distress
Effects of a Bovine Lactoferrin Formulation from Cow's Milk on Menstrual Distress in Volunteers: A Randomized, Crossover Study.
Our study examined the effects of a lactoferrin formulation derived from cow's milk on menstrual symptoms in healthy women.
Conducted as a double-blind, randomized, placebo-controlled trial, we enrolled thirty-five Japanese volunteers who received either the iron-lactoferrin complex or a placebo.
While our findings showed improvements in psychological symptoms related to menstrual distress, such as reduced MDQ scores, other measures—like pain and quality of life—did not vary significantly.
Notably, no side effects were reported, suggesting this treatment could help with psychological discomfort linked to dysmenorrhea.
7
Long-acting contraceptives offer health benefits
Added health benefits of the levonorgestrel contraceptive intrauterine system and other hormonal contraceptive delivery systems.
We discovered that hormonal contraceptives, particularly long-acting systems like the levonorgestrel-releasing intrauterine device, provide significant non-contraceptive health benefits.
These benefits include the treatment of pelvic pain, especially in cases related to endometriosis, as well as management of heavy menstrual bleeding and iron deficiency.
Research highlights that these contraceptives are effective options for addressing various gynecological disorders beyond birth control.
7
Goserelin enhances hemoglobin but not pain
Goserelin acetate 10.8 mg plus iron versus iron monotherapy prior to surgery in premenopausal women with iron-deficiency anemia due to uterine leiomyomas: results from a Phase III, randomized, multicenter, double-blind, controlled trial.
We aimed to understand the impact of adding goserelin acetate to iron treatment in premenopausal women facing iron-deficiency anemia due to uterine fibroids.
In this Phase III trial, participants received either goserelin with iron or just iron over 12 weeks, followed by surgery. While women given goserelin showed higher hemoglobin levels, we didn’t find a significant improvement in symptoms like pelvic pain.
Overall, while goserelin helped with blood levels, it didn't make a noticeable difference in alleviating pelvic discomfort.
References
Lin D, Zhang M, Luo C, Wei P, Cui K, et al. Targeting Ferroptosis Attenuates Inflammation, Fibrosis, and Mast Cell Activation in Chronic Prostatitis. J Immunol Res. 2022;2022:6833867. doi:10.1155/2022/6833867
Ueno HM, Yoshise RE, Sugino T, Kajimoto O, Kobayashi T. Effects of a Bovine Lactoferrin Formulation from Cow's Milk on Menstrual Distress in Volunteers: A Randomized, Crossover Study. Int J Mol Sci. 2016;17. doi:10.3390/ijms17060845
Fraser IS. Added health benefits of the levonorgestrel contraceptive intrauterine system and other hormonal contraceptive delivery systems. Contraception. 2013;87:273. doi:10.1016/j.contraception.2012.08.039
Navvabi Rigi S, Kermansaravi F, Navidian A, Safabakhsh L, Safarzadeh A, et al. Comparing the analgesic effect of heat patch containing iron chip and ibuprofen for primary dysmenorrhea: a randomized controlled trial. BMC Womens Health. 2012;12:25. doi:10.1186/1472-6874-12-25
Muneyyirci-Delale O, Richard-Davis G, Morris T, Armstrong J. Goserelin acetate 10.8 mg plus iron versus iron monotherapy prior to surgery in premenopausal women with iron-deficiency anemia due to uterine leiomyomas: results from a Phase III, randomized, multicenter, double-blind, controlled trial. Clin Ther. 2007;29:1682.